LncRNA H19 induces immune dysregulation of BMMSCs, at least partly, by inhibiting IL-2 production
نویسندگان
چکیده
منابع مشابه
H19 lncRNA regulates keratinocyte differentiation by targeting miR-130b-3p
Aberrant differentiation of keratinocytes has been demonstrated to be associated with a number of skin diseases. A growing number of studies have showed that long noncoding RNAs (lncRNAs) have an important part in gene regulation, however, the role of lncRNAs in keratinocyte differentiation remains to be largely unknown. In the present study, we demonstrated that lncRNA-H19 act as an endogenous...
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متن کاملThe imprinted H19 lncRNA antagonizes let-7 microRNAs.
Abundantly expressed in fetal tissues and adult muscle, the developmentally regulated H19 long noncoding RNA (lncRNA) has been implicated in human genetic disorders and cancer. However, how H19 acts to regulate gene function has remained enigmatic, despite the recent implication of its encoded miR-675 in limiting placental growth. We noted that vertebrate H19 harbors both canonical and noncanon...
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ژورنال
عنوان ژورنال: Molecular Medicine
سال: 2021
ISSN: 1076-1551,1528-3658
DOI: 10.1186/s10020-021-00326-y